13904663128 (Biblioteca BBVA)
Category:1964 births
Category:Living people
Category:Colombian writers
Category:Colombian activistsLocally advanced rectal cancer: preoperative response assessment with dynamic contrast-enhanced magnetic resonance imaging and the role of radiochemotherapy.
The purpose of this article is to determine the potential role of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the preoperative staging of patients with locally advanced rectal cancer and to analyze the value of this approach for determining the optimal approach. Fifty-four patients with locally advanced rectal carcinoma were prospectively examined with DCE-MRI before treatment. Magnetic resonance imaging findings were compared with the results of postoperative histopathologic analysis. In addition, the outcome of patients who underwent DCE-MRI-based multimodal treatment was determined. DCE-MRI depicted locally advanced tumors (n = 22) correctly in 19 of 22 patients. Metastatic lymph nodes (n = 13) were identified with a sensitivity of 81.2% and a specificity of 93.6%. Tumor regression grade (TRG) 1 was correctly assessed in 15 of 22 patients, TRG 2 in 3, TRG 3 in 5, TRG 4 in 1, and TRG 5 in 5. Local recurrence after complete histopathologic remission of the tumor was diagnosed correctly in 1 patient with a TRG of 3 at DCE-MRI. Disease progression was observed in 1 of 5 patients with TRG 4 or 5 and 1 of 15 patients with TRG 3. The treatment-free interval of 25 patients who underwent DCE-MRI-guided multimodal therapy was significantly longer than the time to recurrence of 10 patients who were treated without MRI findings. DCE-MRI has a high diagnostic accuracy for the assessment of locally advanced rectal cancer. The analysis of the preoperative tumor response and the differentiation of TRG 1 from TRG 3 or 4 can influence the approach to rectal cancer treatment.Radioiodine remnant ablation with resin microspheres in patients with Graves' disease: follow-up of 96 cases.
Remnant ablation with 131I-microspheres is a new option for the treatment of residual thyroid tissue in patients with Graves' disease. This study was designed to assess the results of the procedure and to evaluate its benefits and adverse events. This is a retrospective analysis of the first 96 patients referred to our department between September 2000 be359ba680
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